# CPT 45380: Colonoscopy with biopsy

Medicare CPT 45380 pays $479.97 in a non-facility setting and $177.69 in a facility setting under the 2026 Medicare Physician Fee Schedule, before geographic adjustment. After geographic adjustment, state amounts run from $423.81 in Arkansas to $554.38 in Alaska, a 31% spread.

Web page: https://www.med-reveal.com/rates/45380-cpt-fee-schedule
Section: Surgery and Procedures
Billed by: Gastroenterology, General Surgery

## Medicare rates

| | Amount |
| --- | --- |
| National non-facility | $479.97 |
| National facility | $177.69 |
| Conversion factor | 33.4009 |
| Release | 2026 Q4 (effective 2026-10-01) |

## By state

| State | Non-facility | Facility |
| --- | --- | --- |
| Alaska | $554.38 | $232.45 |
| District of Columbia | $550.12 | $194.04 |
| California | $541.86 | $184.18 |
| New Jersey | $531.20 | $190.84 |
| New York | $530.98 | $193.75 |
| Washington | $529.67 | $185.07 |
| Massachusetts | $524.31 | $184.70 |
| Hawaii | $522.02 | $178.33 |
| Connecticut | $512.19 | $186.63 |
| Colorado | $500.69 | $179.07 |
| Maryland | $497.44 | $182.32 |
| Oregon | $495.75 | $177.30 |
| Florida | $494.42 | $191.13 |
| New Hampshire | $492.57 | $177.90 |
| Rhode Island | $492.21 | $179.96 |
| Puerto Rico | $483.61 | $178.01 |
| Virgin Islands | $483.61 | $178.01 |
| Illinois | $481.34 | $189.27 |
| Minnesota | $480.25 | $169.20 |
| Montana | $479.94 | $177.66 |
| Nevada | $477.98 | $175.40 |
| Wyoming | $476.32 | $174.05 |
| Delaware | $474.93 | $176.28 |
| Pennsylvania | $474.81 | $178.72 |
| Texas | $474.18 | $176.59 |
| North Dakota | $471.64 | $169.36 |
| South Dakota | $470.66 | $168.38 |
| Virginia | $469.90 | $172.76 |
| Vermont | $469.54 | $170.29 |
| Arizona | $467.10 | $174.19 |
| Georgia | $466.80 | $178.43 |
| Michigan | $464.34 | $180.50 |
| Maine | $459.15 | $170.33 |
| Utah | $457.54 | $173.40 |
| Wisconsin | $455.56 | $165.98 |
| New Mexico | $453.74 | $176.55 |
| North Carolina | $451.45 | $169.43 |
| South Carolina | $451.26 | $171.96 |
| Missouri | $450.93 | $173.54 |
| Louisiana | $450.18 | $174.20 |
| Ohio | $449.63 | $173.65 |
| Indiana | $447.21 | $167.00 |
| Idaho | $444.57 | $166.48 |
| Nebraska | $444.29 | $165.29 |
| Iowa | $441.76 | $165.17 |
| Tennessee | $441.62 | $166.85 |
| West Virginia | $440.16 | $177.48 |
| Kentucky | $439.92 | $171.20 |
| Kansas | $439.41 | $166.15 |
| Oklahoma | $439.39 | $169.45 |
| Alabama | $430.13 | $165.63 |
| Mississippi | $427.65 | $167.39 |
| Arkansas | $423.81 | $164.15 |

## Related codes

- 40490: Biopsy of lip — https://www.med-reveal.com/rates/40490-cpt-fee-schedule
- 40650: Repair lip, vermilion only — https://www.med-reveal.com/rates/40650-cpt-fee-schedule
- 41010: Frenotomy, lingual — https://www.med-reveal.com/rates/41010-cpt-fee-schedule
- 41112: Excision of lesion of tongue — https://www.med-reveal.com/rates/41112-cpt-fee-schedule
- 41599: Unlisted procedure, tongue/floor of mouth — https://www.med-reveal.com/rates/41599-cpt-fee-schedule
- 42700: Incision and drainage of peritonsillar abscess — https://www.med-reveal.com/rates/42700-cpt-fee-schedule
- 42820: Tonsillectomy and adenoidectomy, under age 12 — https://www.med-reveal.com/rates/42820-cpt-fee-schedule
- 42821: Tonsillectomy and adenoidectomy, age 12 or over — https://www.med-reveal.com/rates/42821-cpt-fee-schedule

Commercial negotiated rates for 45380 by payer and state: https://www.med-reveal.com/solutions/rate-benchmarking

## Sources

- CMS Medicare fee schedules (2026 Q4): https://www.cms.gov/medicare/payment/fee-schedules
