# CPT 88161: Cytopathology, smears, any other source, preparation and screening

Medicare CPT 88161 pays $82.83 in a non-facility setting and $82.83 in a facility setting under the 2026 Medicare Physician Fee Schedule, before geographic adjustment. After geographic adjustment, state amounts run from $73.12 in Arkansas to $95.48 in District of Columbia, a 31% spread.

Web page: https://www.med-reveal.com/rates/88161-cpt-fee-schedule
Section: Laboratory and Pathology

## Medicare rates

| | Amount |
| --- | --- |
| National non-facility | $82.83 |
| National facility | $82.83 |
| Conversion factor | 33.4009 |
| Release | 2026 Q4 (effective 2026-10-01) |

## By state

| State | Non-facility | Facility |
| --- | --- | --- |
| District of Columbia | $95.48 | $95.48 |
| California | $94.96 | $94.96 |
| Alaska | $94.82 | $94.82 |
| Washington | $92.31 | $92.31 |
| New Jersey | $92.01 | $92.01 |
| New York | $91.54 | $91.54 |
| Hawaii | $91.38 | $91.38 |
| Massachusetts | $91.23 | $91.23 |
| Connecticut | $88.41 | $88.41 |
| Colorado | $87.00 | $87.00 |
| Oregon | $86.19 | $86.19 |
| Maryland | $85.91 | $85.91 |
| New Hampshire | $85.39 | $85.39 |
| Rhode Island | $85.20 | $85.20 |
| Minnesota | $84.03 | $84.03 |
| Florida | $84.00 | $84.00 |
| Puerto Rico | $83.54 | $83.54 |
| Virgin Islands | $83.54 | $83.54 |
| Montana | $82.83 | $82.83 |
| Nevada | $82.73 | $82.73 |
| Wyoming | $82.57 | $82.57 |
| North Dakota | $82.24 | $82.24 |
| South Dakota | $82.17 | $82.17 |
| Delaware | $82.03 | $82.03 |
| Texas | $81.84 | $81.84 |
| Pennsylvania | $81.71 | $81.71 |
| Vermont | $81.68 | $81.68 |
| Illinois | $81.59 | $81.59 |
| Virginia | $81.43 | $81.43 |
| Arizona | $80.66 | $80.66 |
| Georgia | $80.04 | $80.04 |
| Maine | $79.55 | $79.55 |
| Wisconsin | $79.39 | $79.39 |
| Michigan | $79.25 | $79.25 |
| Utah | $78.80 | $78.80 |
| North Carolina | $78.09 | $78.09 |
| South Carolina | $77.71 | $77.71 |
| New Mexico | $77.60 | $77.60 |
| Indiana | $77.54 | $77.54 |
| Missouri | $77.43 | $77.43 |
| Louisiana | $77.19 | $77.19 |
| Nebraska | $77.17 | $77.17 |
| Ohio | $77.15 | $77.15 |
| Idaho | $77.07 | $77.07 |
| Iowa | $76.67 | $76.67 |
| Tennessee | $76.41 | $76.41 |
| Kansas | $76.05 | $76.05 |
| Oklahoma | $75.61 | $75.61 |
| Kentucky | $75.48 | $75.48 |
| West Virginia | $74.69 | $74.69 |
| Alabama | $74.22 | $74.22 |
| Mississippi | $73.47 | $73.47 |
| Arkansas | $73.12 | $73.12 |

## Related codes

- 88104: Cytopathology, fluids/washings, smears with interpretation — https://www.med-reveal.com/rates/88104-cpt-fee-schedule
- 88106: Cytopathology, filter method, smears with interpretation — https://www.med-reveal.com/rates/88106-cpt-fee-schedule
- 88108: Cytopathology, concentration technique, smears — https://www.med-reveal.com/rates/88108-cpt-fee-schedule
- 88112: Cytopathology, selective cellular enhancement technique — https://www.med-reveal.com/rates/88112-cpt-fee-schedule
- 88120: Cytopathology, in situ hybridization, urinary tract specimen, computer-assisted — https://www.med-reveal.com/rates/88120-cpt-fee-schedule
- 88121: Cytopathology, in situ hybridization, urinary tract specimen, manual — https://www.med-reveal.com/rates/88121-cpt-fee-schedule
- 88125: Cytopathology, forensic — https://www.med-reveal.com/rates/88125-cpt-fee-schedule
- 88141: Cytopathology, cervical/vaginal, requiring interpretation by physician — https://www.med-reveal.com/rates/88141-cpt-fee-schedule

Commercial negotiated rates for 88161 by payer and state: https://www.med-reveal.com/solutions/rate-benchmarking

## Sources

- CMS Medicare fee schedules (2026 Q4): https://www.cms.gov/medicare/payment/fee-schedules