# CPT 96450: Chemotherapy administration into CNS, requiring spinal puncture

Medicare CPT 96450 pays $160.99 in a non-facility setting and $66.47 in a facility setting under the 2026 Medicare Physician Fee Schedule, before geographic adjustment. After geographic adjustment, state amounts run from $143.89 in Arkansas to $191.28 in Alaska, a 33% spread.

Web page: https://www.med-reveal.com/rates/96450-cpt-fee-schedule
Section: Medical and Therapeutic Services

## Medicare rates

| | Amount |
| --- | --- |
| National non-facility | $160.99 |
| National facility | $66.47 |
| Conversion factor | 33.4009 |
| Release | 2026 Q4 (effective 2026-10-01) |

## By state

| State | Non-facility | Facility |
| --- | --- | --- |
| Alaska | $191.28 | $90.61 |
| District of Columbia | $183.01 | $71.66 |
| California | $179.97 | $68.12 |
| New Jersey | $177.27 | $70.84 |
| New York | $177.26 | $71.81 |
| Washington | $176.35 | $68.59 |
| Massachusetts | $174.71 | $68.51 |
| Hawaii | $173.44 | $65.96 |
| Connecticut | $171.10 | $69.29 |
| Colorado | $167.32 | $66.74 |
| Maryland | $166.49 | $67.94 |
| Florida | $165.77 | $70.93 |
| Oregon | $165.74 | $66.16 |
| Rhode Island | $164.93 | $67.29 |
| New Hampshire | $164.72 | $66.32 |
| Puerto Rico | $162.08 | $66.52 |
| Virgin Islands | $162.08 | $66.52 |
| Illinois | $161.88 | $70.54 |
| Montana | $160.98 | $66.46 |
| Minnesota | $160.75 | $63.49 |
| Nevada | $160.32 | $65.70 |
| Wyoming | $159.78 | $65.25 |
| Pennsylvania | $159.62 | $67.03 |
| Delaware | $159.51 | $66.12 |
| Texas | $159.31 | $66.25 |
| North Dakota | $158.21 | $63.69 |
| South Dakota | $157.89 | $63.36 |
| Virginia | $157.83 | $64.91 |
| Vermont | $157.63 | $64.05 |
| Georgia | $157.15 | $66.97 |
| Arizona | $157.06 | $65.46 |
| Michigan | $156.48 | $67.72 |
| Maine | $154.57 | $64.25 |
| Utah | $154.20 | $65.35 |
| Wisconsin | $153.34 | $62.78 |
| New Mexico | $153.20 | $66.52 |
| South Carolina | $152.29 | $64.95 |
| Missouri | $152.26 | $65.51 |
| North Carolina | $152.25 | $64.06 |
| Louisiana | $152.06 | $65.76 |
| Ohio | $151.88 | $65.58 |
| Indiana | $150.91 | $63.28 |
| Idaho | $150.11 | $63.15 |
| Nebraska | $149.98 | $62.74 |
| Tennessee | $149.25 | $63.33 |
| Iowa | $149.23 | $62.74 |
| West Virginia | $149.22 | $67.08 |
| Kentucky | $148.92 | $64.88 |
| Oklahoma | $148.69 | $64.28 |
| Kansas | $148.57 | $63.12 |
| Alabama | $145.81 | $63.10 |
| Mississippi | $145.15 | $63.76 |
| Arkansas | $143.89 | $62.69 |

## Related codes

- 96360: Intravenous infusion, hydration, initial 31 minutes to 1 hour — https://www.med-reveal.com/rates/96360-cpt-fee-schedule
- 96361: Intravenous infusion, hydration, each additional hour (add-on) — https://www.med-reveal.com/rates/96361-cpt-fee-schedule
- 96365: Intravenous infusion, for therapy/prophylaxis/diagnosis, initial, up to 1 hour — https://www.med-reveal.com/rates/96365-cpt-fee-schedule
- 96366: Intravenous infusion, therapy, each additional hour (add-on) — https://www.med-reveal.com/rates/96366-cpt-fee-schedule
- 96367: Intravenous infusion, additional sequential infusion, up to 1 hour (add-on) — https://www.med-reveal.com/rates/96367-cpt-fee-schedule
- 96368: Intravenous infusion, concurrent infusion (add-on) — https://www.med-reveal.com/rates/96368-cpt-fee-schedule
- 96369: Subcutaneous infusion for therapy/prophylaxis, initial, up to 1 hour — https://www.med-reveal.com/rates/96369-cpt-fee-schedule
- 96370: Subcutaneous infusion, each additional hour (add-on) — https://www.med-reveal.com/rates/96370-cpt-fee-schedule

Commercial negotiated rates for 96450 by payer and state: https://www.med-reveal.com/solutions/rate-benchmarking

## Sources

- CMS Medicare fee schedules (2026 Q4): https://www.cms.gov/medicare/payment/fee-schedules