# HCPCS A4221: Supplies for maintenance of drug infusion catheter, per week

Medicare HCPCS A4221 pays $26.19 on average under the 2026 Q4 Medicare DMEPOS Fee Schedule (non-rural). State amounts run from $25.87 in Wyoming to $32.30 in Puerto Rico, a 25% spread.

Web page: https://www.med-reveal.com/rates/A4221-hcpcs-fee-schedule
Section: Drugs and Biologicals

## Medicare rates

| | Amount |
| --- | --- |
| National non-facility | $26.19 |
| National facility | $26.19 |
| Release | 2026 Q4 (effective 2026-10-01) |

## By state

| State | Non-facility | Facility |
| --- | --- | --- |
| Puerto Rico | $32.30 | $32.30 |
| Hawaii | $30.06 | $30.06 |
| Virgin Islands | $29.07 | $29.07 |
| Alaska | $28.95 | $28.95 |
| Alabama | $25.87 | $25.87 |
| Arizona | $25.87 | $25.87 |
| Arkansas | $25.87 | $25.87 |
| California | $25.87 | $25.87 |
| Colorado | $25.87 | $25.87 |
| Connecticut | $25.87 | $25.87 |
| Delaware | $25.87 | $25.87 |
| District of Columbia | $25.87 | $25.87 |
| Florida | $25.87 | $25.87 |
| Georgia | $25.87 | $25.87 |
| Idaho | $25.87 | $25.87 |
| Illinois | $25.87 | $25.87 |
| Indiana | $25.87 | $25.87 |
| Iowa | $25.87 | $25.87 |
| Kansas | $25.87 | $25.87 |
| Kentucky | $25.87 | $25.87 |
| Louisiana | $25.87 | $25.87 |
| Maine | $25.87 | $25.87 |
| Maryland | $25.87 | $25.87 |
| Massachusetts | $25.87 | $25.87 |
| Michigan | $25.87 | $25.87 |
| Minnesota | $25.87 | $25.87 |
| Mississippi | $25.87 | $25.87 |
| Missouri | $25.87 | $25.87 |
| Montana | $25.87 | $25.87 |
| Nebraska | $25.87 | $25.87 |
| Nevada | $25.87 | $25.87 |
| New Hampshire | $25.87 | $25.87 |
| New Jersey | $25.87 | $25.87 |
| New Mexico | $25.87 | $25.87 |
| New York | $25.87 | $25.87 |
| North Carolina | $25.87 | $25.87 |
| North Dakota | $25.87 | $25.87 |
| Ohio | $25.87 | $25.87 |
| Oklahoma | $25.87 | $25.87 |
| Oregon | $25.87 | $25.87 |
| Pennsylvania | $25.87 | $25.87 |
| Rhode Island | $25.87 | $25.87 |
| South Carolina | $25.87 | $25.87 |
| South Dakota | $25.87 | $25.87 |
| Tennessee | $25.87 | $25.87 |
| Texas | $25.87 | $25.87 |
| Utah | $25.87 | $25.87 |
| Vermont | $25.87 | $25.87 |
| Virginia | $25.87 | $25.87 |
| Washington | $25.87 | $25.87 |
| West Virginia | $25.87 | $25.87 |
| Wisconsin | $25.87 | $25.87 |
| Wyoming | $25.87 | $25.87 |

## Related codes

- A4211: Supplies for self-administered injections — https://www.med-reveal.com/rates/A4211-hcpcs-fee-schedule
- A4212: Non-coring needle or stylet with or without catheter — https://www.med-reveal.com/rates/A4212-hcpcs-fee-schedule
- A4213: Syringe, sterile, 20cc or greater, each — https://www.med-reveal.com/rates/A4213-hcpcs-fee-schedule
- A4215: Needle, sterile, any size, each — https://www.med-reveal.com/rates/A4215-hcpcs-fee-schedule
- A4216: Sterile saline/water, metered dose dispenser, 10ml — https://www.med-reveal.com/rates/A4216-hcpcs-fee-schedule
- A4217: Sterile water/saline, 500ml — https://www.med-reveal.com/rates/A4217-hcpcs-fee-schedule
- A4222: Infusion supplies for external drug infusion pump, per cassette/bag — https://www.med-reveal.com/rates/A4222-hcpcs-fee-schedule
- A4223: Infusion supplies not used with external infusion pump, per day — https://www.med-reveal.com/rates/A4223-hcpcs-fee-schedule

Commercial negotiated rates for A4221 by payer and state: https://www.med-reveal.com/solutions/rate-benchmarking

## Sources

- CMS Medicare fee schedules (2026 Q4): https://www.cms.gov/medicare/payment/fee-schedules